Sept. 24, 2020: Dr. Priyamvada Acharya: CryoEM of the SARS-CoV-2 spike
Автор: CryoEM Service Centers
Загружено: 2020-10-21
Просмотров: 619
Описание: The COVID-19 pandemic has spurred world-wide scientific research collaborations and efforts to find effective interventions. Since early this year, like many other research groups, we sought to repurpose our knowledge and skills to the study of the SARS-CoV-2 Spike (S) protein. In this talk, I will present our work over the past few months to setup pipelines for biophysical, biochemical and structural studies of the SARS-CoV-2 S protein. In a methods-focused presentation, I will review our cryo-EM structural determination pipeline with particular emphasis on specimen optimization of SARS-CoV-2 S protein samples. Finally, I will describe the close network of collaborations at the Duke Human Vaccine Institute that are working to develop COVID-19 vaccines and therapies, and the role that structural biology and cryo-EM play in it.
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