X-rays of Osteogenesis imperfecta, brittle bone disease

Описание: Osteogenesis imperfecta (OI), also known as brittle bone disease, is a genetic disorder characterized by fragile bones that fracture easily. On X-rays, OI has several distinctive features that reflect abnormal bone formation and remodeling.

📊 Radiographic Features of Osteogenesis Imperfecta
Feature Description
General bone appearance Bones appear thin, gracile, and osteopenic (low density).
Frequent fractures Multiple healed fractures with deformities, angulation, and callus formation.
Bone deformities Bowing of long bones (especially femur and tibia), “accordion-like” appearance due to repeated fractures.
Skull changes Wormian bones (extra small bones within cranial sutures).
Spine Vertebral compression fractures, scoliosis, and platyspondyly (flattened vertebrae).
Ribs Multiple fractures with beading or deformity.
Pelvis Coxa vara (hip deformity), acetabular protrusion.
🖼️ Typical X-ray Findings
Long bones: Thin cortices, bowing, multiple fracture lines, and callus formation.

Skull: Presence of Wormian bones in sutures.

Spine: Flattened vertebrae with compression fractures.

Chest: Rib fractures with irregular healing.

🔑 Key Takeaways
OI X-rays show fragile, thin bones with multiple fractures and deformities.

Severity varies depending on the type of OI (mild → few fractures, severe → multiple deformities).

Radiographs are essential for diagnosis but are combined with clinical features (blue sclera, hearing loss, family history

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