Heart Failure Drugs | Diuretics | Cardiovascular Pharmacology | V-Learning

Описание: sqadia.com gives you CHF pharmacology today in which we will be discussing the drugs to treat congestive heart failure. Drugs used in congestive heart failure pharmacology pdf is also given in the resources tab for your help so do not forget to check that out too.

▬ 📃 Heart Failure ▬▬▬▬▬▬▬▬▬▬
Heart failure is characterized by the heart’s inability to pump an adequate blood supply to the body. Without sufficient blood flow, all major body functions are disrupted. Heart failure is a condition or a collection of symptoms that weaken your heart.

In some people with heart failure, the heart has difficulty pumping enough blood to support other organs. Other people may have a hardening and stiffening of the heart muscle itself, which blocks or reduces blood flow to the heart. It can be either Acute or Chronic.

👉 Heart Failure Causes
Heart failure is often the result of several problems affecting the heart at the same time.

Conditions that can lead to heart failure include:
🟠 Coronary heart disease
🟠 High Blood Pressure
🟠 Cardiomyopathy
🟠 Heart Rhythm Problems
🟠 Damaged heart valves
🟠 Congenital Heart Disease

All these factors are discussed in detail in this video so do not forget to watch till the end.

▬ 📜 Heart Failure Drugs ▬▬▬▬▬▬▬▬▬▬
The following categories of drugs are considered remedies for heart failure. They include:
🔵 Vasodilators
🔵 Diuretics
🔵 Inotropic Drugs
🔵 Sympathomimetic Drugs

Learn about their details in the video.

👉 Heart Failure Inotropic Drugs
Digoxin increases the force of cardiac contraction in the failing heart. This benefit has often been doubted in patients with chronic heart failure in sinus rhythm, but recent clinical trials have shown that digoxin can reduce the symptoms of heart failure in patients who are already receiving diuretics and ACE inhibitors. Digoxin is particularly indicated in heart failure caused by atrial fibrillation.

👉 Heart Failure Drugs Electrical Effects
These are due to a complicated mixture of direct and indirect actions.

🟢 Direct Actions - In atrial and ventricular cells, the action potential and refractory period are shortened, because the increased intracellular Ca2+ stimulates the potassium channels.

🟢 Indirect Actions - Digoxin increases central vagal activity and facilitates muscarinic transmission in the heart.

👉 Heart Failure Sympathomimetic Drugs
These activate cardiac β‐receptors and stimulate adenylyl cyclase, an effect mediated by a G‐protein called Gs. The resulting rise in cyclic adenosine monophosphate (cAMP) activates cAMP-dependent protein kinase, which leads to phosphorylation of the L‐type Ca2+ channels and an increase in the probability of their opening. This increases the influx of Ca2+ and hence the force of myocardial contraction.

▬ 🎬 5500+ sqadia.com Medical Videos ▬▬▬▬▬▬▬▬▬▬
👩🏻‍⚕️ Accessible Medical Student Education 24/7/365
💡 Simplifying Medical Learning
💪 Study Hard, Dream Big, Achieve More