Unintentional Weight Loss

Описание: Unintentional weight loss is not just a symptom — it is a cardinal manifestation of disease. In this video, we break down involuntary weight loss exactly the way it is approached in Harrison’s Principles of Internal Medicine, with clinical reasoning rather than rote lists.

This video is ideal for MBBS students, interns, residents, and clinicians who want to understand why weight loss occurs, not just memorize causes. We explore the pathophysiologic framework behind weight loss: reduced intake, malabsorption, increased metabolic demand, and inflammatory catabolic states. Special emphasis is placed on the distinction between starvation and cachexia, a concept frequently tested and often misunderstood.

You will learn how to approach a patient with unexplained weight loss using history-driven diagnosis, red-flag identification, and rational investigation — exactly as expected in exams and clinical practice. Malignancy-associated weight loss, chronic infections like tuberculosis, endocrine causes such as hyperthyroidism, and psychiatric causes like depression are all discussed within a unifying logic.

This is not a beginner overview. The focus is on clinical thinking, conceptual clarity, and exam-relevant reasoning aligned with Harrison and Davidson. If you want medicine to make sense as a system rather than a checklist, this video is for you.