Organelle Crosstalk: Mitochondria & Lysosomes in Immune Cell Fate and Function
Автор: Elabscience
Загружено: 2026-01-26
Просмотров: 38
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The event was held live on January 15, 2026. Watch the full recording on demand.
Mitochondria–lysosome crosstalk functions as a core signaling axis regulating immune cell metabolism, stress adaptation, and cell fate, mediated by Ca²⁺ flux, ATP–mTORC1 signaling, and ROS at organelle contact sites. Disruption of this crosstalk contributes to neurodegeneration, metabolic disorders, and cancer, while T-cell–focused studies reveal critical effects on Treg fitness, CD8⁺ T-cell effector function, immune activation, and PANoptosis, supported by advanced tools for monitoring mitochondrial health, and inflammatory signaling, in immunometabolism research.
In this webinar, Dr. Eqra Hafeez shared expert perspectives on:
🔬 Organelle contact sites as immune signaling hubs
⚡ Ca²⁺, ROS, and mTORC1 integrate metabolic and stress signals
🧬 Mechanistic regulation of Treg and CD8⁺T-cell metabolism
🧪 Insights into neurodegeneration, cancer, and metabolic disease models
🛠 Validated tools for mitochondrial and lysosomal health
For technical inquiries, contact us via email
[email protected]
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