PRR: Toll-like Receptors (TLRs) – Innate Immunity and Signaling Pathways - IMMUNOLOGY

Описание: In this lecture, we explore the Toll-like receptors (TLRs), a crucial family of pattern recognition receptors (PRRs) that enable innate immune cells to detect pathogens and tissue damage.

📌 What you will learn in this video:
-) PAMPs and DAMPs: how the innate immune system detects pathogens and damage
-) The structure of TLRs: LRR domains, transmembrane and TIR domains
-) Positioning of TLRs: plasma membrane vs endosomes
-) Ligands of TLRs: bacterial, viral, and fungal components
-) Key receptors: TLR-1, TLR-2, TLR-4, TLR-5, TLR-6, TLR-3, TLR-7, TLR-8, TLR-9
-) TLR signaling pathways: MyD88/MAL, TRIF/TRAM, IRF and NF-κB activation
-) Clinical and functional implications in infection and immunity

📚 Who is this video for?
-) Medical and biomedical students preparing for exams in immunology, microbiology, and pathology (university level-video)
-) Educators and lecturers, who can use this resource as classroom support
-) Anyone passionate about immunology and molecular medicine

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🔎 Optimized hashtags and keywords
#Immunology #InnateImmunity #TLRs #TollLikeReceptors #PRRs #PAMPs #DAMPs #NFkB #IRF #AgoràScienzeBiomediche #MedicalEducation #ImmunologyLecture