How does oncology drug induce cardiotoxicity? Overview: mechanism & clinical guidelines (ESMO) 2022

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This video is an overview on drug-induced cardiotoxicity on its mechanism of toxicity, clinical guidelines on its risk factors, steps on how to prevent cardiotoxicity, monitoring of symptoms, detection of biomarkers and how to manage the cardiotoxicity at the early stages.

Drugs eg anthracyclines, tyrosine kinase inhibitors, human epidermal growth factor inhibitors, proteosomal inhibitors and immune checkpoint inhibitors are covered in the video. The wide range of cardiotoxicity diseases can be a result of these drugs such as heart failure, arrhythmia, hypertension, atrial fibrillation, myocarditis, with monitoring with echocardiogram, troponin and B natriuretic peptide levels.

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-- Content of this video -----
0:00 - Intro + Which drugs can cause cardiotoxicity
4:21 - Mechanism of cardiotoxicity
12:54 - Clinical guidelines & general prevention steps, exercise
18:15 - Anthracyclines
29:59 - HER2 inhibitors, VEGF inhibitors, mTOR inhibitors, tyrosine kinase inhibitors, proteasome inhibitors, ibrutinib, immune checkpoint inhibitors
36:14 - How to manage cardiotoxicity
42:02 - Drug-induced arrhythmia

The video content is mainly tailored for pharmacy school students but students from medical, biomedical, high school etc are also welcomed to view the videos.

If you're a patient/family member/any member of the public who wants to learn more about the medication/disease that you're interested in, you're welcomed to view the videos.
Any health concerns, do consult your doctor as there's a lot of factors into consideration before the doctor chooses the most suitable medication for you.

WHO AM I:
Hi! I’m Dr Yuen, a pharmacist @ pharmacology lecturer in a pharmacy school. I’m reorganising my lectures for my students, hopefully it’ll be useful for you too in your revision. A major upgrade will be done soon on the video style, hopefully it’ll be more interesting for you to watch it till the end for the information. Stay tuned & you’re welcomed to subscribe the channel for video updates.

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