If you can’t kill it, make it stronger? - Sarah Robinson
Автор: Otago Medical Research Foundation
Загружено: 2018-12-10
Просмотров: 92
Описание:
Research undertaken by Sarah Robinson with support from Professor Kurt Krause, Biochemistry, School of Biomedical Sciences.
Otago Medical Research Foundation – McQueen Scholar
To discover and design new tuberculosis treatments, we need a way of testing drug performance that will reliably identify effective antibiotics. As a result, summer researchers in the department of biochemistry are working to increase the activity of a tuberculosis enzyme so that the effect of inhibitors can be more clearly seen.
Tuberculosis is responsible for more deaths globally than HIV, malaria, and smallpox combined. The University of Otago is involved in designing new treatments for antibiotic-resistant strains, targeting an enzyme shown to be critical for tuberculosis survival and spread.
As the enzyme is inactive once removed from the cell, mutations have been designed to increase its observable activity. Summer researchers are now developing a test to identify promising drug candidates that appear to inhibit enzyme function. We alsohope to make the test reproducible on a micro-scale, to minimise the resources used in each trial.
Повторяем попытку...
Доступные форматы для скачивания:
Скачать видео
-
Информация по загрузке:
