Locked-in Syndrome - Gradual Spontaneous Recovery

Описание: Locked-in syndrome may be incomplete (patients have some voluntary movements) or total, where persons are completely motionless including absence of vertical eye movements. The condition is typically caused by vertebrobasilar infarction with pontine infarction. This video (beginning 00:30) illustrates a 22-year man who developed acute basilar artery infarction attributed to dehydration with Factor V Leiden, causing a large pontine and cerebellar infarct despite aggressive treatment with IV thrombolysis and endovascular thrombectomy. He became locked-in but awake and attentive, with a gaze preference to the left and minimal horizontal eye movements to the right. Over the next 18-24 months he gradually improved to near normal function; imbalance due to spastic ataxia remained and he retained a mild residual horizontal ophthalmoplegia and left facial weakness in an upper motor neuron pattern, but most other motor functions recovered well. For full case details see http://ja.ma/1HSCege.