Keynote - Computational GPCR Pharmacology
Автор: British Pharmacological Society
Загружено: 2025-08-11
Просмотров: 74
Описание:
David Gloriam is a Professor in Computational Receptor Biology at the University of Copenhagen where he leads a research cluster for GPCR function and drug discovery and a Pharmaceutical Data Science unit. His group runs the GPCRdb database where ~4,000 researchers each month to retrieve reference data and access online tools for analysis, visualization and experiment design.
He got his PhD from Uppsala University, Sweden including the bioinformatic identification of 24 novel human G protein-coupled receptors. He later identified physiological hormones of such undercharacterised ‘orphan’ receptors and functional probes for a range of receptors. He made two postdocs in the UK at the EMBL-European Bioinformatics Institute and GlaxoSmithKline. In 2018 he joined the University of Copenhagen, where he has received an ERC Starting Grant, Lundbeck Foundation Fellowship and Novo Nordisk Foundation Ascending Investigator awards.
Gloriam is a corresponding member of the Nomenclature Committee of the International Union of Pharmacology (IUPHAR). He is one of the coordinators of recommendations to describe ligand bias towards signalling probes and safer drugs and his group recently developed an online resource of biased ligands and pathway effects to advance the biased signalling field.
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