Q:1.3 Answer is in description below...
Автор: Metabolism AMC
Загружено: 2025-09-02
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Blue book MCQ: 1.3 Ans: B is correct
Although resolution of C. difficile pseudomembranous colitis occurs in a proportion of cases, most cases require specific treatment for persisting symptoms.
Metronidazole is the preferred antimicrobial as treatment and is the most effective and least expensive of available agents. Metronidazole is best given orally in a course of at least six days (B is correct).
Vancomycin is also effective but, because of the risk of inducing vancomycin
resistance in bowel organisms (e.g. vancomycin-resistant enterococci), is avoid ed in all but the most difficult cases.
Ciproftoxacin is more appropriate for 'travellers' diarrhoea, Salmonella enteritis, and shigellosis.
Chloramphenicol has a broad spectrum of activity, but use is limited by its toxicity.
Other treatment guidelines are to maintain hydration, avoid opiates and anti- peristaltic agents which may mask symptoms, and attendance to faecal-oral and hand hygiene.
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