The "Sugar" Secret Behind Psoriasis Inflammation
Автор: Science News
Загружено: 2025-12-30
Просмотров: 5
Описание:
Researchers have discovered a surprising sugar-based mechanism that drives inflammation in psoriasis. Immune cells shed their protective outer layer of sugars—called the glycocalyx—to migrate into inflamed skin, challenging long-held beliefs about how immune cells move during disease.
Published in Science Signaling, this study from Lancaster University and the University of Manchester reveals that it’s not just blood vessel cells modifying their sugar coatings—immune cells actively shed their own glycocalyx to enter tissues. This subtle molecular change could reshape how we approach treatments for psoriasis and other inflammatory diseases.
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