Colwyn Headley | Bioengineering Mitochondria for Transplantation Therapy
Автор: Foresight Institute
Загружено: 2025-08-25
Просмотров: 387
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Colwyn Headley | Bioengineering Mitochondria for Transplantation Therapy
Bio: Dr. Colwyn “CoCo” Headley earned his B.S. in Microbiology and Ph.D. in Biomedical Sciences (Immunology) from The Ohio State University, followed by a Postdoctoral Fellowship in Cardiovascular Medicine at Stanford University. His research explores the intersection of aging-associated mitochondrial dysfunction and immune regulation, focusing on uncovering novel mechanisms underlying immune-mediated cardiovascular diseases, such as abdominal aortic aneurysms and peripheral artery disease.
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Abstract: Dr. Headley’s work leverages innovative approaches in mitochondrial bioengineering and mitochondrial transplantation, including his latest innovation: antibody-mitochondria conjugates, which enable targeted mitochondrial delivery to specific cell populations, enhancing therapeutic precision and efficacy for aging-related pathologies.
Timecodes
00:00 Welcome and Introduction
01:12 Understanding Mitochondrial Dysfunction
04:50 Mechanisms of Mitochondrial Transplantation
06:36 Experimental Methods and Findings
09:27 Mitochondrial Transplantation in T-Cells
16:44 Exploring Mitochondrial Transplantation in Macrophages
19:52 Challenges and Innovations in Mitochondrial Delivery
27:39 MIT Attack System
29:26 Bioengineering Mitochondria: Future Prospects
30:37 Targeted Delivery for Immune System
32:18 MIT Attack System for Cardiovascular and Space Applications
33:59 Collaborations and Future Research Directions
34:29 Q&A: Targeting Specific Cell Types
43:35 Q&A: Enhancing Mitochondria
48:13 Q&A: Mitochondria in Space
49:47 Closing Remarks and Final Thoughts
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