Active Surveillance for

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5:17 The Number of people on Active Surveillance is increasing?
5:37 Proper to diagnose someone with an insignificant tumor?
5:53 Do I have "cancer"?
6:28 What is cancer?
8:05 PSA is the best screening biomarker in the history of oncology if used well
8:22 Newer screening practices
9:33 Does this mean Grade Group 1, 3+3, Dr. Cooperberg says not cancer?
10:34 GG1 is not a normal finding, but A.S. is recommended
11:58 Continuum of Biology
12:57 Arbitrary line drawn for cancer
13:45 What if we don't call it cancer?
14:49 Why the largest PSA screening trial failed
19:25 Should men go for PSA screening?
20:57 Median PSA is 0.7 between 45 and 50
21:22 If it's under 1.0, you're done
22:30 PSA values vary
23:23 What does act on PSA mean?
24:50 Liquid tests
25:54 Why not have everyone get an MRI?
26:23 What inter-observer variability exists with MRI's?
32:27 Cooperberg screening policy
33:59 DRE (Digital Rectal Exam)
40:26 How should a man choose his localized treatment?
43:15 Is there an age limit for Active Surveillance?
45:45 Mental health considerations
49:31 Confirmatory biopsy
52:01 Why can't everyone diagnosed get a BRCA/Genetic test?
56:10 What do we do differently now we know you have a BRCA mutation?
1:00:25 What about Pathology?
1:01:10 Sub-types of Pattern 4
1:02:38 Cribriform patterns
1:04:14 All GS 3+4 is not created equal
1:05:25 Is PSA density of 0.15 a valid cutoff for Active Surveillance?
1:05:50 Intraductal/large cribriform patterns for Active Surveillance?
1:06:54 Cancer is driven by the worst corner of it
1:08:06 Most Gleason 7's sent for genomic test
1:08:34 Intraductal worst pattern followed by cribriform
1:09:24 DRE's for Active Surveillance?
1:09:48 How often for PSA's/MRI's?
1:10:26 Active Surveillance 2023 (one opinion)
1:12:59 How do you choose your urologist?
1:15:00 Do PSA kinetics matter?
1:16:05 MEAL trial
1:18:22 What about exercise?
1:19:35 What about testosterone replacement therapy?
1:21:32 What about the two types of PSA tests?


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