Post-Stroke Depression & Dementia: The Hidden Link to Cognitive Decline
Автор: 普羅心腦醫學
Загружено: 2026-01-29
Просмотров: 1
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Stroke Recurrence: Post-stroke depression (PSD) has been confirmed as an independent risk factor for stroke recurrence. The one-year recurrence rate is significantly higher in patients with PSD compared to non-depressed patients (28.3% vs. 18.9%), with an odds ratio of 1.64.
Cognitive Impairment: PSD is a strong predictor of dysfunction across multiple cognitive domains. The impact is most significant in visuospatial skills (OR = 6.10) and language processing (OR = 5.09).
Neuroanatomical Correlates: Research indicates a significant correlation between lesions involving cortico-subcortical structures and the development of PSD.
https://pubmed.ncbi.nlm.nih.gov/41271640/
Cankaya S, Safa SS, Karakus A, Savcili M, Hanoglu L, Mardinoglu A, Cetin FE, Kumral E, Yulug B. Depression is an independent risk factor for stroke reccurence and cognitive impairment in stroke patients. Transl Psychiatry. 2025 Nov 21;15(1):492. doi: 10.1038/s41398-025-03706-8. PMID: 41271640; PMCID: PMC12639108.
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