MEG and EEG to detect Interictal HFOs in Pediatric Epilepsy | Protocol Preview

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy - a 2 minute Preview of the Experimental Protocol

Christos Papadelis, Eleonora Tamilia, Steven Stufflebeam, Patricia E. Grant, Joseph R. Madsen, Phillip L. Pearl, Naoaki Tanaka
Boston Children's Hospital, Harvard Medical School, Fetal-Neonatal Neuroimaging and Developmental Science Center, Division of Newborn Medicine, Department of Medicine; Massachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging; Boston Children's Hospital, Harvard Medical School, Division of Epilepsy Surgery, Department of Neurosurgery; Boston Children's Hospital, Harvard Medical School, Division of Epilepsy and Clinical Neurophysiology, Department of Neurology;

High Frequency Oscillations (HFOs) have emerged as presurgical biomarkers for the identification of the epileptogenic zone in pediatric patients with medically refractory epilepsy. A methodology for the noninvasive recording, detection, and localization of HFOs with simultaneous scalp electroencephalography (EEG) and magnetoencephalography (MEG) is presented.

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