Dr. Ciro Franzese on SBRT and Single-Fraction RT in Prostate Cancer | ESTRO 2025

Описание: At ESTRO 2025, Prof. Ciro Franzese, Radiation Oncologist at Humanitas San Pio X and Associate Professor at Humanitas University in Milan, presented two key updates in prostate cancer radiotherapy.

✅ In the OLIGOCARE trial interim analysis, involving over 2,000 oligometastatic patients, he showed that combining SBRT with systemic therapies (including chemo, immunotherapy, hormonal, or targeted therapy) does not increase the risk of severe toxicity, supporting its safety in real-world multimodal settings.
✅ In his second presentation, Prof. Franzese explored the emerging role of single-fraction SBRT for localized prostate cancer. Early results from trials like ONE-SHOT, PROSINT, and ABRU indicate comparable disease control and low toxicity compared to conventional 5-fraction SBRT, with potential benefits for elderly or frail patients.
✅ He also highlighted promising data from the POPART trial, which investigates SBRT after prostatectomy as a salvage option, showing encouraging early oncologic and toxicity outcomes.

#ESTRO2025 #SBRT #ProstateCancer #OligometastaticCancer #OligoCare #StereotacticRadiotherapy #RadiationOncology #SingleFractionSBRT #HumanitasUniversity

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