Workshop on Network Pharmacology (Part-2): On-site Session on Network Construction using Cytoscape
Автор: Center for Complementary and Integrative Health
Загружено: 2021-12-28
Просмотров: 24592
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Network pharmacology approach has many applications in drug discovery and repurposing. It attempts to predict drug action through interactions with multiple targets using computational methods on available data. The mechanistic plausibility of natural products used in traditional medicine systems like Ayurveda can be explored using the network pharmacology approach. Botanicals based on Ayurveda and Traditional Chinese Medicine have been successfully explored for their putative targets in different diseases and disorders using network pharmacology.
The researchers of AYUSH Center of Excellence, CCIH, ISHS, SPPU are working with the tools of network pharmacology. The network pharmacology tool utilizes the reported data from databases of compound structures, protein targets, diseases, and biological pathways. It predicts the probable association of bioactives with disease/pathway through protein targets. The on-site session was focused on the data management and network construction using Cytoscape.
Mr Akash Saggam, a Research Fellow and Ph.D. Scholar from AYUSH Center of Excellence demonstrated the use of Cytoscape for network construction. The complete workshop material can be found here: https://drive.google.com/drive/folder...
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