Grignard Reaction-Ester/Mechanism & Product (1° or 3° Alcohol)/Alkyl Halides|

Описание: Grignard Reaction with Ester | Complete Mechanism Explained | Chemistry Wallah

The Grignard Reaction with Esters is one of the most powerful transformations in Organic Chemistry, widely tested across MDCAT, NEET, JEE, ETEA, and international competitive exams. This lecture explains, in a clear and exam-oriented way, how Grignard reagents convert esters into tertiary alcohols, why two moles of RMgX are required, and how the ketone intermediate forms and reacts further.

This video strengthens conceptual understanding and helps students solve MCQs, mechanism questions, and product-prediction problems with confidence.


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🌟 What You Will Learn

✔ Nature and Reactivity of Grignard Reagents

Polar carbon–magnesium bond

Strong nucleophilic and basic character

Structure, preparation, and behavior


✔ Why Esters Undergo Two Consecutive Attacks

Electrophilic carbonyl carbon

OR group acting as a leaving group

Formation of a ketone intermediate

Immediate second nucleophilic attack


✔ Complete Step-by-Step Mechanism

1. First nucleophilic attack by RMgX → tetrahedral intermediate


2. Collapse of intermediate → formation of ketone


3. Second attack by RMgX


4. Acidic hydrolysis → formation of tertiary alcohol



✔ Final Product Explanation

Why esters always give tertiary alcohols

Stability of intermediates

Comparison with aldehydes and ketones (written without greater-than symbols)



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🎯 Exam-Focused Outcomes

By the end of this lecture, students will be able to:

Predict products when esters react with Grignard reagents

Understand intermediate structures

Solve mechanism-based MCQs quickly

Recognize reaction patterns in synthesis problems

Apply concepts in board exams and competitive tests



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🧪 Key MCQ Concepts Covered

Reactivity order explained in words (aldehydes are more reactive than ketones, and ketones are more reactive than esters)

Reason for two-step addition

Importance of acidic hydrolysis

Why tertiary alcohols are formed

Grignard reagent as a strong nucleophile


These points frequently appear in MDCAT, NEET, JEE, ETEA, NUMS, NUST and other major exams.


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📘 Why This Lecture Matters

This lecture enhances understanding of:

Organic reaction mechanisms

Synthetic pathways

Carbonyl chemistry

Formation of complex alcohols


Essential for both medical and engineering exam aspirants.


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🌍 About Chemistry Wallah

We deliver high-quality, conceptual chemistry lectures for FSc, MDCAT, NEET, JEE, ETEA, and international students. Our focus is clarity, mechanism understanding, and real exam problem-solving.


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💬 Final Words

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