[TALK 12] Structural Biology 2.0: Crystallography - Dom Bellini - Biophysical Techniques Course 2022

Описание: Structural Biology 2.0: Crystallography
Speaker: Dom Bellini, MRC Laboratory of Molecular Biology, UK

The LMB X-ray Crystallography Facility offers instruments and expertise to help LMB researchers who succeeded in obtaining crystal hits to collect X-ray diffraction data of good enough quality to solve the structure.

In this video, Dom details the crystallographic project workflow from sample quality, crystallisation, crystal soaking, crystal harvest, to in-house X-ray and synchrotron data collection data, processing and structure validation. He also discusses the impact of prediction programs like AlphaFold and cryo-EM on structural biology and compares the utility of X-ray crystallography with nmr, cryo-EM and AlphaFold for different targets.

The X-ray Crystallography Facility is run by Dom Bellini. Read more about the facility here: https://www2.mrc-lmb.cam.ac.uk/resear...

You can find more videos from the LMB 2022 Biophysics Techniques Lecture series here:    • Biophysical Techniques Course 2022  

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