Neurotransmitter and Its Classification - Explaining Excitatory and Inhibitory Neurotransmitters
Автор: Aamna memon
Загружено: 2021-12-26
Просмотров: 774
Описание:
In this video, we'll be discussing the different types of neurotransmitters and their classification. We'll also be discussing the effects of these neurotransmitters on the body and how they're regulated.
If you're interested in neuroscience or want to learn more about neurotransmitters, then this video is for you! By the end of this video, you'll have a better understanding of what neurotransmitters are and how they work, as well as a better understanding of the classification of neurotransmitters.
Neurotransmitter And Its Classification | Excitatory and Inhibitory Neurotransmitter | Acetylcholine
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It is signaling molecule
Secreted by neuron
Body's chemical messengers.
More than 100 neurotransmitters have been identified in the body
Electrical synapse – scientist believed they are present in brain
Later through histological examination – 20-40nm gap is found between neuron – synaptic cleft
They may be chemical messengers involved to carry message.
in 1921 German pharmacologist Otto Loewi confirmed that neurons can communicate by releasing chemicals.
acetylcholine
First discovered neurotransmitter
Neuron that contain acetylcholine called cholinergic
Ionotropic –nicotinic acetylcholine receptor
Metabotropic - muscarinic acetylcholine receptor
Responsible for activating muscles
regulates the activities happening in the brain, which is related to learning and memory.
Low level cause Alzheimer’s disease
Acetocholiestrase enzyme
dopamine
Monitor memory and motor control
Monoamine neurotransmitter and catecholamine
Low level cause dementia
High level cause anxiety, mood swing and attention disorders.
Tyrosine - L-dopa - decarboxylated to dopamine
Act on g-protein coupled receptor
Enables motivation, learning, and pleasure
epinephrine
It is monoamine neurotransmitter
excitatory neurotransmitter
regulates metabolism and blood pressure.
raise glucose levels in the blood.
High level cause sleep issues
this neurotransmitter is used to cure cardiac arrest, superficial bleeding, and anaphylaxis
norepinephrine
It is monoamine neurotransmitter and catecholamine.
It is also Hormone
produced by the adrenal medulla as a hormone.
Concentrated in pons and medulla
excitatory chemical messenger
focus and attention.
also known as the stress hormone and noradrenaline.
Some of the side effects of Norepinephrine are the increase in glucose uptake, cold feeling, irritation, skin changes and balance difficulties.
glutamate
Amino acid neurotransmitter
Excitatory neurotransmitter
Excitatory
synaptic plasticity (important for learning and memory), formation of neural networks during development and repair of the CNS
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