Oral Neuroactive Steroids
Автор: NEI Psychopharm
Загружено: 2023-07-28
Просмотров: 2013
Описание:
The modulation of GABA-A receptors by neuroactive steroids (e.g. zuranolone) might contribute to the pathophysiology of depression. Here, Dr. Andrew Cutler and Dr. Roger McIntyre review the data and results from clinical studies of the investigational drug under development, zuranolone. Zuranolone, an investigational oral neuroactive steroid with a novel mechanism of action as a positive allosteric modulator of GABA-A and is being evaluated as a 14-day, rapid-acting, once-daily, oral treatment in adults with major depressive disorder (MDD) and postpartum depression (PPD).
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