ARISTOTLE (2011): Apixaban vs Warfarin in Patients with Atrial Fibrillation

Описание: ARISTOTLE (2011): Apixaban vs Warfarin in Patients with Atrial Fibrillation
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⛔️Disclaimer: This post is for educational and informational purposes only and is not intended for medical advice, diagnosis or treatment, nor to replace medical care. For patient care, always consult a healthcare professional for medical advice, diagnosis, treatment, and management. Information presented here, has been adapted from the original study, cross referenced, and presented to the best of the authors ability; however, errors may still be present.
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📍 Population: Afib or aflutter with stroke RF: 75 y/o+, prior stroke/TIA/systemic embolism, symptomatic HF within 3 months or LVEF less than 40%, DM2, HTN
🧪 Intervention: Apixaban vs warfarin
🎯 Outcome: Stroke or Systemic embolism, major bleeding, all cause mortality
✅ Key Takeaway: Apixaban is superior to warfarin in decreasing stroke/systemic embolism, major bleeding, all cause mortality.
⚠️Short follow up period (under 2 years), Sponsored by Bristol-Myers Squibb/Pfizer
🔗Original study DOI: 10.1056/NEJMoa1107039
🔗ACC: https://www.acc.org/Latest-in-Cardiol...
🔗2MinuteMedicine: https://www.2minutemedicine.com/the-a...