4. Neoplastic Proliferation of WBC 🩸⚡ | Leukemias & Lymphomas Overview | Hematopathology

Описание: 📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:-t.me/conceptualmedicine009
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/

This lecture explains neoplastic proliferation of white blood cells, a core topic in hematopathology and general pathology, essential for MBBS students, USMLE Step 1 aspirants, NEET PG, and FMGE candidates 🩸📚. Neoplastic WBC proliferation refers to clonal, uncontrolled growth of hematopoietic cells, arising from genetic mutations affecting cell proliferation, differentiation, and apoptosis ⚡. The lecture introduces the broad classification into leukemias, characterized by diffuse bone marrow and peripheral blood involvement, and lymphomas, which primarily present as tissue-based masses in lymph nodes or extranodal sites 🔥. Key concepts such as acute vs chronic leukemias, myeloid vs lymphoid lineage, blast crisis, and marrow failure leading to anemia, thrombocytopenia, and infections are explained to build strong diagnostic logic 🧠. Molecular and cytogenetic abnormalities like Philadelphia chromosome, oncogene activation, and tumor suppressor gene loss are briefly correlated to pathogenesis and disease behavior. Clinical relevance includes leukostasis, immunosuppression, and organ infiltration. This session builds strong conceptual clarity and pattern recognition essential for MCQs, classification-based questions, and clinicopathological correlations in hematology ❤️✨.

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