Desmopressin (ddavp): Nclex-rn Question Review

Описание: If you're NEW subscribe! → https://goo.gl/n2b5aj

In today's video we'll review desmopressin, a synthetic hormone used to treat nocturnal enuresis and certain clotting disorders. It may be given in the nose, by injection into a vein, by mouth, or under the tongue. Desmopressin works by limiting the amount of water that is eliminated in the urine; that is, it is an antidiuretic.

It works at the level of the renal collecting duct by binding to V2 receptors, which signal for the translocation of aquaporin channels via cytosolic vesicles to the apical membrane of the collecting duct. The presence of these aquaporin channels in the distal nephron causes increasing water reabsorption from the urine, which becomes passively re-distributed from the nephron to systemic circulation by way of basolateral membrane channels.

Desmopressin also stimulates release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

Thanks for the support, and make sure you SUBSCRIBE for more NCLEX question reviews!

Follow the channel on:

IG:   / nurseessentials  
Twitter:   / nurseessential  
Facebook:   / nurseessentials  

Media: #howtopassnclex .
.
.
#howtopassnclex #oxygentherapy #nursingstudent #nursing #nursingschool #nursinglectures