Erik Werner - Using a Bayesian model for clinical study design and blinded data review

Описание: At IRLAB we develop novel treatments for Parkinson’s disease. A central part of this work is the planning and analysis of clinical trials. A key benefit of using a Bayesian approach for this is that the models used for planning trials can be continuously refined as blinded data from the trials become available. This allows simulation of a range of plausible study outcomes that are consistent with the data observed, which is helpful for optimizing both study size and the plan for how to analyze results at the end of the trial.