Michael Martin, MD: SRSF2/TET2 co-mutations & molecular profiling impact in MDS/AML
Автор: Moffitt Cancer Center
Загружено: 2025-12-06
Просмотров: 20
Описание: During #ASH25, Michael Martin presents a study showing that in patients with SRSF2 and TET2 co-mutations, additional myelodysplasia-related gene mutations are common and linked to anemia, monocytosis and significantly poorer survival, particularly in MDS. ASXL1 predicted worse outcomes, while BCOR, STAG2 and ZRSR2 mutations were more frequent in AML, underscoring the prognostic value of expanded molecular profiling.
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