A decedent is found with gastric contents and blood positive for amitriptyline but no drug in urine
Автор: The.Mad.Forensic.Scientist
Загружено: 2025-11-07
Просмотров: 191
Описание:
This toxicological profile suggests that the death occurred relatively soon after the ingestion of amitriptyline, indicating a very short Post-Absorption Interval.
The presence of amitriptyline (a tricyclic antidepressant) in the gastric contents (stomach) confirms recent ingestion, while the presence in blood shows that absorption into the circulatory system has begun. The critical absence of the drug in the urine suggests the drug has not yet had sufficient time to undergo significant metabolism and subsequent renal excretion. This pattern is often seen in acute overdose cases where the fatal event occurred within the first few hours of drug intake, before the body's elimination processes could fully establish.
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