Webinar: Innovative Methods Advancing Discovery and Characterization of Antibodies

Описание: Contact us: https://carterra-bio.com/contact/

Part I: Multiple Innovative Technologies & Platforms Empower Antibody Discovery

Abstract: The rapid development of the antibody industry depends on the application of new technologies and platforms. This talk introduces Biointron’s many new technologies and platforms, ranging from antibody development, functional assays, to antibody optimization, such as VHH discovery platform, FCMES affinity maturation platform, AbDrop single B-cell sorting platform, etc. The talk also demonstrates Carterra’s remarkable contributions to these platforms, which have greatly improved the efficiency, quality, and throughput. Numerous cases are displayed to share with the audience.

Part II: Discovery and Characterization of Multi-Specific Antibodies: New Capabilities and Workflow

Abstract: Selection of bi- and tri-specific binders often require the screening of large combinatorial sample sets derived from panels of single domain binders. The Carterra LSA platform makes analyzing the binding properties of these molecules straightforward and requires minimal amounts of mAb sample and antigen. The affinity of the binders to the targets can be measured in several assay formats and used to verify the independence and activity of each binding site for hundreds of clones. Along with the binding kinetics and specificity measurements, the LSA enables large scale epitope binning to ensure diverse sets of clones are being carried forward to functional evaluation.

In this webinar, you’ll learn about:
• VHH discovery platforms
• Affinity maturation
• AbDrop single B-cell sorting
• Binding kinetics and specificity
• High-definition epitope binning using HT-SPR
• Screening crude periplasmic extracts