Molecular targets in salivary gland cancers: a comprehensive genomic analysis of 1,666 cases
Автор: VJOncology
Загружено: 2022-09-15
Просмотров: 300
Описание:
Abirami Sivapiragasam, MD, Upstate Medical University, Syracuse, NY, provides an overview of a comprehensive genomic analysis of molecular targets in 1,666 cases of salivary gland cancers using the FoundationOne platform to assess molecular profiling. Patients with salivary duct carcinoma were observed to have the highest number of targetable treatment options. Approximately 32% of patients of these patients have PIKC3 alteration which can be considered for treatment with alpelisib. 60% of patients have HER2 amplification and 10% had high tumor mutational burden (TMB). This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.
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