Statistical models used for GWAS (Lecture 7)
Автор: H3ABioNet
Загружено: 2018-09-25
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Statistical models used for GWAS
The seventh and last lecture of the H3ABioNet 2018 GWAS lecture series will cover different types of GWAS depending on data designs: Population-based GWAS (for case/control design or for quantitative traits) and Family-based GWAS (for independent trio data or large pedigrees). This lecture will also provide an overview of test statistics for multi-marker association testing in both type of GWAS. It will discuss the problem of multiple testing, the principal of family wise error rate (FWER) and some proposed methods for P-values correction. The lecture will finally present a set of tools to perform GWAS and to represent results.
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