HIV-Associated Neurocognitive Disorders (HAND) | A Clinical Medicine Brief

Описание: 🧠 NEURO101: HIV-Associated Neurocognitive Disorders (HAND) | Clinical Medicine Brief | Pro-PA Podcast
In this NEURO101 Clinical Medicine Brief, we’re diving into HIV-Associated Neurocognitive Disorders (HAND)—a spectrum of cognitive, motor, and behavioral changes seen in people living with HIV. Though often underdiagnosed, HAND is a critical neurologic consideration for both PANCE prep and clinical practice.

🎯 In this episode, we’ll cover:

What is HAND? From Asymptomatic Neurocognitive Impairment (ANI) to HIV-Associated Dementia (HAD)

Pathophysiology: Chronic immune activation, viral reservoirs in the CNS

Common symptoms: Memory loss, attention deficits, slowed processing, gait disturbance

Diagnosis: Clinical evaluation, exclusion of other causes, neuropsych testing

Importance of ruling out opportunistic infections (e.g., PML, toxoplasmosis, CMV)

MRI findings: Often nonspecific but may show white matter changes

Treatment: ART optimization, CNS-penetrating regimens, cognitive support strategies

Clinical pearls: Recognizing HAND in long-term survivors, older adults, and low CD4 counts

This episode equips you to recognize and manage one of HIV’s most underappreciated complications—before it gets missed.

🎧 Listen on Spotify: https://open.spotify.com/show/2gn5uJP...
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