SPARC Seminar Series: Dr. Don Bolser

Описание: Central circuits that process superior laryngeal nerve sensory feedback: It’s complicated.
Donald Bolser, PhD.
University of Florida

Perturbations of peripheral sensory systems with devices have the potential to profoundly modify the behavior of central control circuits. These actions can lead to therapeutic effects or deleterious side effects mediated by the CNS that hinder device development. The functional organization of these circuits, especially those that mediate vagal reflexes, remains poorly understood. We have investigated the central pathways that mediate a simple reflex from the superior laryngeal nerve, the laryngeal adductor reflex. These efforts have revealed a control system that exerts tight regulation of reflex excitability and is not easily predictable based on knowledge of the afferent system alone.

Learn more on the SPARC Portal: https://sparc.science
Functional mapping of peripheral and central circuits for airway protection and breathing [Project Link](https://sparc.science/about/projects/...)

SPARC is a NIH-approved, HEAL-compliant repository that accepts data about the peripheral nervous system and systems physiology. As an AWS Open Data Partner, all data and models stored on SPARC are freely accessible.

Interested in contributing data? learn more here: https://sparc.science/share-data

About SPARC:
Formed in 2015, the SPARC DRC is a dedicated international consortium working together to advance scientific understanding and improve clinical outcomes by providing a leading platform for integrating data, knowledge, computational modeling, and mapping of the peripheral nervous system, its CNS interactions, and related physiological processes. Initiated with funding from the U.S. National Institutes of Health Common Fund’s SPARC program (award numbers: OT2OD030541, OT3OD025348, OT3OD025347, and OT3OD025349), the SPARC Portal is now an open repository.