BioInfo Meet #2: Aditya Badola - Meta-pangenomics, and other tongue twisters...

Описание: Aditya Badola, Bioinformatician@Perseus Biomics:   / aditya-badola  

Why is microbial diversity key to our survival?
In an increasingly sanitized world, declining microbial diversity threatens our health. Understanding microbial interactions is crucial.

I introduce metapangenomics, combining pan-genome analysis and metagenomics to study microbial uniqueness across habitats. Traditional sequencing faces cost and resource challenges, but DynaMAP, a sequencing-free technology by Perseus Biomics, offers a low-cost, rapid solution (~3 hours). It provides strain-level resolution and long reads (80–90 Kbp), enabling precise abundance profiles and pangenome analysis.

By identifying accessory gene clusters, we uncover unique microbial interactions and their functional roles. This approach reveals evolutionary history, biochemical pathways, and gut health secrets—like why a Mediterranean diet outperforms processed foods.

Join me to explore how metapangenomics and DynaMAP are revolutionizing microbial research for a healthier future.