Remote desktop: Use several monitors, but not all

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How is it possible to utilize just a portion of a multi-monitor system when employing remote desktop?
Remote Desktop has the capability to function across several monitors. Ordinarily, there is an option in the Remote Desktop Connection to "Use all monitors for remote session," and it can be enabled.
In scenarios where this is the case, all existing monitors are engaged. Should you have in excess of two monitors and wish to use only a subset of them, it can be done without difficulty, although this option is not provided through the graphical user interface.