Bioluminescent Bacteria and Impact of Pneumococcal Virulence Factors | Protocol Preview

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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria - a 2 minute Preview of the Experimental Protocol

Malek Saleh, Mohammed R. Abdullah, Christian Schulz, Thomas Kohler, Thomas Pribyl, Inga Jensch, Sven Hammerschmidt
University of Greifswald, Department Genetics of Microorganisms, Interfaculty Institute for Genetics and Functional Genomics;

Streptococcus pneumoniae is the leading pathogen causing severe community-acquired pneumonia and responsible for over 2 million deaths worldwide. The impact of bacterial factors implicated in fitness or virulence can be monitored in real-time in an acute mouse pneumonia or bacteremia model using bioluminescent bacteria.

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