Study of Pyrogen Test for Parenteral Product by Rabbit Method using Ex-pharm Software

Описание: Study of Pyrogen Test for Parenteral Product by Rabbit Method using Ex-pharm Software

Please click the links for the In-vivo study protocols: https://www.researchsop.com/2022/04/L...

Study of Pyrogen Test for Parenteral Product using Rabbit Method
Description :
In this video, we explore the Pyrogen Test for Parenteral Products using the Rabbit Method with the help of Ex-Pharm Simulation Software. The pyrogen test is crucial for ensuring the safety of injectable drugs by detecting substances that cause fever when introduced into the body.
We begin by explaining what pyrogens are, including the difference between endotoxins (toxic components of the bacterial cell wall) and other pyrogenic substances. Next, we discuss commonly used pyrogen detection tests: the Limulus Amebocyte Lysate (LAL) test, which specifically detects bacterial endotoxins, and the Monocyte Activation Test (MAT), which identifies a broader range of pyrogens, including non-endotoxin materials.
The main focus is on the Rabbit Pyrogen Test, a classical and still widely accepted method. We walk through the detailed steps involved in conducting the test: preparation, dosing rabbits with the test sample, measuring their body temperature changes, and interpreting the results.
This comprehensive tutorial is ideal for pharmacy students, researchers, and professionals involved in pharmaceutical quality control and safety testing.

Keywords:
Pyrogen test, Rabbit pyrogen test, Parenteral product testing, Ex-Pharm software, What is pyrogen, Endotoxin, Limulus Amebocyte Lysate test, LAL test, Monocyte Activation Test, MAT test, Pyrogen detection methods, Pharmaceutical quality control, Injectable drug safety, Fever-inducing substances, Bacterial endotoxins, Pyrogen testing procedure, Rabbit method steps, Pharmaceutical microbiology, Drug safety testing, Parenteral product safety, Simulation software tutorial, Researchneeds, Researchsop