Influence of deprivation on severity and prognosis of patients admitted to the ICU: IVOIRE study

Описание: DOI : 10.1186/s13613-020-0637-1


The prospective, multicentre, observational IVOIRE cohort study (n=1,000 patients across 10 French ICUs) investigated socioeconomic deprivation's impact on initial severity and prognosis in critically ill patients, using the EPICES score (Additional file 1) to quantify deprivation status. Key statistical findings revealed significant negative associations: multivariable linear regression (after multiple imputation) showed deprivation reduced SAPS II scores by β = -0.82 (95% CI: -1.15 to -0.49) and increased mortality risk by β = 0.38 (95% CI: 0.12 to 0.64) in logistic regression (after multiple imputation), with comparable effects observed in complete-case analyses (Tables S2 and S4). Deprivation status also correlated with higher healthcare utilization costs and altered ICU management patterns (Table S3). The study concluded that socioeconomic deprivation independently worsens initial severity (as measured by SAPS II) and mortality in ICU patients, with the EPICES score providing a validated metric for assessing deprivation-related disparities in critical care outcomes, highlighting urgent clinical implications for equitable resource allocation and targeted interventions in underserved populations.