Can you use Vitamin C and Retinoids together?

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Hi! Welcome to Maelove.

Today we address the question, can I use Vitamin C and Retinoids together?

The answer is yes you can use these ingredients together in your skincare routine.
There have been some clinical studies where both ingredients were used in a skincare routine and the results were positive.
One is from Herndon and colleagues in 2016 in the Journal of Drugs in Dermatology.

They had 44 testers with hyperpigmented and photodamaged skin use a 30% vitamin C product and a 0.5% retinol product for 12 weeks.
By weeks 8 and 12, the researchers found significant benefits to skin clarity and evenness, fine lines and wrinkles, hyperpigmentation, and skin smoothness as graded by a clinician.

If you’re new here, my name is Jackie and I’m the CEO and Chief Product Obsessor at Maelove.


Sources mentioned:
Herndon JH Jr, Jiang LI, Kononov T, Fox T. An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin. J Drugs Dermatol. 2016 Apr;15(4):476-82. PMID: 27050703.

Seité S, Bredoux C, Compan D, Zucchi H, Lombard D, Medaisko C, Fourtanier A. Histological evaluation of a topically applied retinol-vitamin C combination. Skin Pharmacol Physiol. 2005 Mar-Apr;18(2):81-7. doi: 10.1159/000083708. PMID: 15767769.

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This content is provided as part of our commitment to bringing science-based information to the public, and it is intended to offer general scientific background on the topic. However, health is complex, and individual cases can vary significantly. We strongly encourage you to consult with a healthcare provider who can diagnose and prescribe treatments specifically tailored to your needs.

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