Sperm Mixed Antiglobulin Reaction (MAR) Test | Male Fertility Testing | Semen Analysis | Biomedical

Описание: The Mixed Antiglobulin Reaction (MAR) test is an immunological assay used to detect the presence of antibody-coated sperm. It identifies whether antibodies (typically IgA and IgG) are attached to the surface of sperm, indicating an
immunological cause of infertility. MAR is a qualitative or semi-quantitative test.

The principle of the MAR test involves mixing the patient's semen sample with latex particles coated with human immunoglobulin (IgG or IgA). If antibodies are present on the sperm surface, they will bind to the latex particles, causing agglutination (clumping). The percentage of sperm bound to the latex particles correlates with the severity of antibody coating.

Negative MAR Test:
• A low percentage (typically less than 40%) of sperm bound to latex particles.
• Indicates a low likelihood of significant sperm antibody presence.
• Immunological factors are less likely to be contributing to infertility.

Positive MAR Test:
• A high percentage (typically ≥40%) of sperm bound to latex particles.
• Suggests a significant presence of sperm antibodies.
• Indicates that immunological factors are likely contributing to infertility.
• The higher the percentage, the more severe the antibody coating.

#sperm #spermanalysis #spermhealth #spermcount #counting #fertility #infertility #positive #negative #nhs #doctor #doctors #gender #genderreveal #fertilityjourney #fertilitytreatment #lowcount #infertilityproblems #infertilityjourney #infertilityreason #infertilitydiet #diet #fertilityspecialists #testing #lab #laboratory #laboratorio #laboratorymedicine #medicine #medical #medicalstudent #medico #health #healthtips #healthylife #life #laboratoryscience #familyplanning #family #womenhealth #menhealth #menshealth #biomedicalscientist