HIRN Webinar: Circulating Extracellular Vesicles in Type One Diabetes (T1D)
Автор: Human Islet Research Network
Загружено: 2024-10-29
Просмотров: 153
Описание:
Thursday, October 24, 2024
Presentations by:
Raghu Mirmira, MD, PhD, University of Chicago
Ernesto Nakayasu, PhD, Pacific Northwest National Laboratory
Emily Sims, MD, Indiana University School of Medicine
Topics discussed:
A highly sensitive proteomics platform enables extracellular vesicle (EV) analysis from minimal plasma volumes.
Proteomics analysis of auto-antibody positive plasma identifies potential biomarkers.
Beta cell EVs carrying PD-L1 reduce CD8 T cell activation.
Plasma EV PD-L1 cargo correlates with residual C-peptide in AAb+ individuals and in individuals with new-onset T1D
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