The Immune Reboot: Dual-Action Antibodies Wake Dormant T-Cells
Автор: g Fun Facts online
Загружено: 2026-01-12
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This episode of G Fun Facts Online discusses the 'Immune Reboot,' a groundbreaking cancer treatment breakthrough in January 2026. It focuses on dual-action antibodies that reawaken dormant CD8+ cytotoxic T-cells, overcoming T-cell exhaustion, a long-standing hurdle in immunotherapy. The new therapies, developed by the University of Southampton and ModeX Therapeutics, either super-cluster co-stimulatory receptors like CD27 or act as tetraspecific T-cell engagers with built-in co-stimulation (CD28), effectively 'igniting' the immune response rather than just releasing it. These innovations promise to be more effective against solid tumors and offer a safer, off-the-shelf alternative to CAR-T therapy.
https://gfunfacts.online/article/c787...
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