NACFC 2022 | S11: Delivery to the Lung: The Right Technology, the Right Cell
Автор: Cystic Fibrosis Foundation
Загружено: 2022-11-18
Просмотров: 370
Описание:
Initiatives to address cystic fibrosis genetic repair require advanced knowledge of the cellular targets most relevant to clinical benefit. As a case in point, CFTR is highly expressed in pulmonary ionocytes. However, little is known about the physiological or functional significance of ionocyte biology to normal lung tissue, or the importance of CFTR rescue for mitigating CF lung disease. This symposium is designed to consider respiratory cell types that must be genetically corrected in order to benefit CF lungs. Presentations directed towards ionocyte biology, CF submucosal glands, basal cells, etc. will be discussed. The session reviews the role and potential impact of these and other cell types as targets for CF intervention
Originally recorded November 3, 2022.
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