Aceclidine: Mechanism of Action in Presbyopia Treatment | PHARMACOLOGY Explained

Описание: Struggling with reading glasses? Presbyopia — the age-related loss of near vision — affects over 100 million adults in the US alone. But a brand-new FDA-approved eye drop could change everything.

In this video, we break down how aceclidine works in presbyopia, why it’s different from pilocarpine (Vuity), and what the clinical trials revealed. You’ll learn:

• What happens to the eye in presbyopia
• How aceclidine improves near vision with the “pinhole effect”
• Key differences between aceclidine vs pilocarpine drops

Whether you’re a healthcare professional, a pharmacology student, or just curious about new eye treatments, this clear explanation will help you understand the science behind aceclidine and its impact on presbyopia treatment.

Disclaimer: This YouTube channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is for informational purposes only. This should not be considered as a substitute for healthcare professional advice. Please consult a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. The statements about specific products are not to diagnose, treat, cure, or prevent disease.

References:
1. Grzybowski, A., Markeviciute, A., & Zemaitiene, R. (2020). A Review of Pharmacological Presbyopia Treatment. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), 9(3), 226–233. https://doi.org/10.1097/APO.000000000...
2. Zhang, X., Xiong, X., Zhang, H., Huang, T., & Zhou, X. (2024). Pilocarpine in the Treatment of Presbyopia: Progress, Issues, and Future Prospects. Drugs & aging, 41(11), 897–906. https://doi.org/10.1007/s40266-024-01...
3. Lievens, Chris W. OD; Hom, Milton M. OD, FAAO; McLaurin, Eugene B. MD; Yuan, Jiang PhD; Safyan, Eleonora BS; Liu, Haixia MD, PhD. Pilocarpine HCl 1.25% for treatment of presbyopia after laser vision correction: pooled analysis of two phase 3 randomized trials (GEMINI 1 and 2). Journal of Cataract & Refractive Surgery 50(1):p 57-63, January 2024. | DOI: 10.1097/j.jcrs.0000000000001313
4. https://biotuesdays.com/2021/07/27/le...
5. https://www.pharmacytimes.com/view/vi...
6. https://medicalxpress.com/news/2025-0...
7. https://ir.lenz-tx.com/news-events/pr...
8. https://news.abbvie.com/2021-10-29-U-...

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