Linvoseltamab (LYNOZYFIC ) - a BCMA x CD3 Bispecific Antibody for Multiple Myeloma

Описание: Linvoseltamab (Lynozyfic™) is a BCMA-directed bispecific antibody approved for the treatment of relapsed or refractory multiple myeloma. In this video, we explain what linvoseltamab is, how Lynozyfic works, and why this therapy represents an important advance in T-cell–redirecting immunotherapy for myeloma.

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Links:
• What is CRS lesson on YT:    • CRS Explained: Understanding Cytokine Rele...  
• What is ICANS lesson on YT:    • ICANS (Immune Effector Cell-Associated Neu...  
• Linvoseltamab website: https://www.lynozyfic.com/

0:00 Introduction
0:11 How does linvoseltamab work?
1:22 How is linvoseltamab administered and dosed
3:25 What is the administration schedule for linvoseltamab?
4:05 Can linvoseltamab be given in a community setting?
4:31 What premedications are given?
5:43 What are the main side effects?
6:21 What are the symptoms of cytokine release syndrome (CRS)
8:08 What other side effects are seen?
8:43. What is ICANS and how common is ICANS?
10:40 Are there any delayed neurotoxicities?
11:35 Should patients be concerned about infections?
13:23 Besides CRS, ICANS and increased infection risks, what other side effects are seen?
15:16 What prophylactic medications are recommended?
17:19 What are recommendations on vaccination?
18:34 What trial confirmed the approval of linvoseltamab?
19:26 What is the linvoseltamab REMS program?
20:16 Can patients respond to linvo if they had previous BCMA-directed therapy?
22:44 What is the role of the caregiver?
23:33 Who is eligible to receive linvoseltamab?
24:52 What is the linvoseltamab wallet card?
25:25 What is the LYNOZYFIC Surround Program?

#MultipleMyeloma #Linvoseltamab #Lynozyfic #BCMA #BispecificAntibody #MyelomaTreatment #CancerImmunotherapy #TCellRedirectingTherapy #RelapsedRefractoryMyeloma


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