Speaking of MolBio Podcast -The hidden language of RNA – how epigenetics is shaping medicine

Описание: In this episode of Speaking of Mol Bio, Dr. Gudrun Stengel, CEO of Alida Biosciences, shares how her startup is revolutionizing RNA research with proximity barcoding. Learn how this novel tech uncovers RNA modifications linked to diseases and hear her journey as a first-time founder.

Alida Biosciences: alidabio.com
Molecular Biology Virtual Lab: thermofisher.com/molbiovirtuallab
Speaking of Mol Bio Podcast: https://www.thermofisher.com/us/en/ho...

Chapter:
00:00 - Welcome to Speaking of Mol Bio 
Host Steve Lewis introduces our guest, Dr. Gudrun Stengel, and sets the stage for a fascinating discussion on groundbreaking molecular biology research. 

00:58 - Innovative RNA Analysis Tools  
Learn about tools for analyzing RNA modifications and their applications in diagnostics, therapeutics, and synthetic biology. 

01:46 - Understanding Proximity Barcoding for RNA Detection 
A deep dive into proximity barcoding and its role in identifying RNA modifications that are silent in standard sequencing. 

06:07 -The Importance of RNA Modifications in Disease Research 
Dr. Stengel explains the diverse functions of RNA modifications and their implications for understanding diseases such as cancer, Alzheimer's, and diabetes. 

10:16 - Life as a Founder: Gudrun’s Perspective 
Insight into Dr. Stengel's transition from industry researcher to startup founder, balancing the excitement of experimentation with the challenges of managing a growing team. 

16:12 - The Future of mRNA Vaccines and Modifications 
Exploring how RNA modifications could revolutionize the design of mRNA vaccines and synthetic biology applications. 

17:41 - Discovering New Frontiers in RNA Research 
Discussing untapped areas of RNA research and their potential to reshape diagnostics and therapeutics. 

20:28 - Streamlined Solutions for Researchers 
Using reverse transcription in proximity barcoding to identify the location of RNA modifications. 

24:25 - Challenges and Opportunities in RNA Modification Analysis 
Identifying gaps in RNA analysis methods and envisioning the future of multiomics research. 

27:58 - How Many 'Omics' Are There? 
Dr. Stengel counts the different layers of multiomics and reflects on their interconnected roles in cellular processes. 

28:55 - Persistence and Passion in Scientific Innovation 
Dr. Stengel shares her personal philosophy and advice for aspiring researchers aiming to contribute to the betterment of society. 

31:15 - Closing Remarks & Next Episode Tease 
Wrapping up the podcast with final reflections and anticipation for future episodes. 



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