New Study Crushes “One Size Fits All” Diet?

Описание: New diet trial looks at precision nutrition, the right diet for each person.

Many diets can provide benefits. E.g. trials on low fat vs low carb show similar weight loss and metabolic improvements over the long run.

Why do some people do better on diet A and others on diet B?

Overweight volunteers split randomly between 2 diets with same amount of calories but differing in fat content. 34% of calories from fat vs 28%

fat was replaced with protein.

nutrition trials often try to keep protein constant because it affects satiation and intake. many nutrients affect satiation. Fat, fiber etc.

Fiber: in the higher fat diet was a bit under 30g fiber a day and the lower fat diet was a bit over 30g.

supplement of B-glucan (fiber in oats and barley).

Other than that, carbs were kept constant. ~44% of calories from carb in both groups

the fat they added was monounsaturated fat. PUFAs and SFA were kept constant at ~8% of calories each

the higher fat diet had more olive oil and olives. the lower fat diet had more low fat dairy like low fat yogurt and cheese.

They were on the diets for 3 months

They looked for improvements in metabolic parameters like fasting insulin, glucose & insulin after a meal, triglycerides and markers of inflammation

Some people improved on the lower fat diet, some on the higher fat diet.

Insulin resistance= when organs don´t respond normally to insulin so they resist taking up glucose from circulation

You can have insulin resistance in the liver while muscles are still more insulin sensitive. they estimated Insulin resistance in liver and muscle.

people with Insulin resistance in the liver predominantly did better on the higher fat diet. metabolic parameters improved. on the lower fat diet there was no significant change. with muscle Insulin resistance they saw improvement on the lower fat diet, no significant change on higher fat

changes in the microbiome? unsaturated fat improves liver function so its good for liver Insulin resistance?

caloriess didnt differ significantly. changes didn´t seem to be explained by overall weight loss.

there was a small weight loss of ~2% in all groups, weight loss per se didn´t explain it.

Fat loss trended. Visceral fat didnt appear different

gynoid fat, fat accumulated in the hips, thighs and breasts, differed significantly.

muscle Insulin resistance lost more gynoid fat on lower fat diet and saw metabolic improvements on that diet. liver Insulin resistance= less gynoid fat and better metabolic markers on higher fat

precision nutrition is in its infancy

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References:
1-https://jamanetwork.com/journals/jama...
2- the new trial https://www.cell.com/cell-metabolism/...
3-https://www.vox.com/2016/11/2/1345343...
4-https://pubmed.ncbi.nlm.nih.gov/24439...

Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.

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0:00 What is Precision Nutrition?
1:09 New trial
4:08 The results
6:05 Body weight and body fat
7:40 What does it mean?
8:26 Is Precision Nutrition ready for the limelight?
10:00 Best of both worlds