P53 animation - tumor supressor gene animation
Автор: Shomu's Biology Academy
Загружено: 2016-04-14
Просмотров: 51255
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P53 tumor supressor Animation - This lecture video explains about the role of p53 in cell cycle regulation and the onset of cancer. P53 gene encodes in tumour suppressor protein p53 tumour suppressor has a negative effect on cell growth and division p53 protein functions in many different pathways are so well in contention to subscribe to the p53 gene is expressed to produce the p53 protein in a normal so the protein is on stable so the amount of p53 protein are so small decisions are introduced into the DNA p53 protein is stabilised by a mechanism that is like currently understood this leads to an increase in the amount of p53 protein and was so p53 even binds to the promoter of Jean W a and activates the expression of the gene product is a protein called P 20 1P 21 now has an effect on the cell cycle. The progress from G1 to us phase 1 or G1 cycling proteins bind to the enzyme cycle independent kinase CDK and activates it and CDK then phosphorylate ski proteins needed for progression of the cell into us peak we want is present binds to cycle and CDK complex blogging kinase activity the absence of kinase activity prevents the transition of the cell into us rests G1 phase and I is as programmed cell death of apoptosis both also p53 are inactivated in the cell of the tumour suppressor p53 is present to activate the W.A. of one gene NOP 21 has made CDK activity is not blocked so so cannot be arrested in G1 phase and so will proceed into us phase will undergo apoptosis and congressional cells with DNA damage through cell cycle control cells to accumulate additional mutations and hence increase the probability of cancer. Thank You for watching our videos from Biology Animation Videos channel. This channel is created to compile animated biology lectures and videos from different animation sources. None of these videos are created by us. we just organize them and place them in YouTube for your understanding so If you want to know details about these animation please see the credit section for knowing the original content developer and please convey privilege and gratitude to them. Thank You.
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