Interview to Guido Kroemer - New Frontiers In Biological And Environmental Determinants Of Aging

Описание: Given the relevance of aging in Swiss society — with the Ticino Region having the highest longevity in Europe – the Forum aimed to promote awareness about aging in both the scientific community and the population. The Forum entitled “New Frontiers in the biological and environmental determinants of aging” brought together international experts from various disciplines (Biology, Psychology and Epidemiology) to discuss aging from their perspectives.

Prof. Guido Kroemer
"Three criteria that must be met for each hallmark of aging: (1) the time-dependent, manifestation of alterations accompanying the aging process, (2) the possibility to accelerate aging by experimentally accentuating the hallmark, and—most decisively—(3) the opportunity to decelerate, halt or reverse aging by therapeutic interventions on the hallmark. During recent years we and others have accumulated data indicating that disabled autophagy fulfills these criteria in thus far that (i) autophagy progressively declines with age in model organisms, (ii) genetic or pharmacological inhibition of autophagy accelerates aging, as well as the manifestation of age-related diseases including cancer, cardiovascular and degenerative diseases, and (iii) experimental autophagy enhancement extends healthspan and lifespan."

The event was organized by IBSA Foundation and the Bellinzona Institutes of Science (Bios⁺) ‪@instituteforresearchinbiom4620‬ .