ESC Guidelines: Pharmacotherapy for HFrEF (Arabic Version)

Описание: After we learned how to diagnose CHF, now it's time for treatment.
So let's start with prescribing optimal medications for a patient with HFrEF.

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
https://www.escardio.org/Guidelines/C...


PARADIGM-HF trial, Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
https://www.nejm.org/doi/full/10.1056...


TRANSITION Study, NT-proBNP Response to Sacubitril/Valsartan in Hospitalized Heart Failure Patients With Reduced Ejection Fraction.
https://www.jacc.org/doi/abs/10.1016/...


EMPEROR-Reduced trial, Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
https://www.nejm.org/doi/full/10.1056...


DAPA-HF trial, Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
https://www.nejm.org/doi/full/10.1056...


CHARM-Alternative trial, Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors
https://www.thelancet.com/journals/la...


Val-HeFT trial, A Randomized Trial of the Angiotensin-Receptor Blocker Valsartan in Chronic Heart Failure
https://www.nejm.org/doi/full/10.1056...


SHIFT trial, Ivabradine and outcomes in chronic heart failure. A randomised placebo-controlled study
https://www.thelancet.com/journals/la...


VICTORIA trial, Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
https://www.nejm.org/doi/full/10.1056...


GALACTIC-HF trial, Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure
https://www.nejm.org/doi/full/10.1056...